Tumor I Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form.Question 1) An 11-year-old presents with 6-month history of groin pain. X-rays and biopsy specimen are shown in Figure A and B. What is the etiology of the lesion?Tumor Question 1) Figure A Tumor Question 1) Figure B Select the Correct AnswerViral InfectionG(s) alpha mutationT(11;22)T(x;18)Post TraumaticCorrect Answer: G(s) alpha mutation Explanation: Fibrous dysplasia is a common benign skeletal lesion that may involve one bone (monostotic) or multiple bones (polyostotic) and occurs throughout the skeleton with a predilection for the long bones, ribs, and craniofacial bones. The etiology of FD has been linked to an activating mutation in the gene that encodes the alpha subunit of stimulatory G protein. The etiology for Paget’s is unknown but suspected to be linked to a viral infection. T(11;22)- Ewing’s sarcoma T(x;18) –synovial sarcoma. References: Source:AAOS SAE Questions Aboulafia AJ, Kennon RE, Jelinek JS. Begnign bone tumors of childhood. J Am Acad Orthop Surg. 1999 Nov-Dec;7(6):377-88. doi: 10.5435/00124635-199911000-00004. PMID: 11505926. Wrong Answer: Please try again! Submit Post navigation Next QuestionIntroduction
